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Murine vagus nerve recordings after cytokine injection
Internal Dataset- Authors
- Theodoros ZanosHarold SilvermanTodd LevyTea Tsaava6 more author(s)...
- Description
These datasets were generated during a study to develop methods to isolate and decode specific neural signals to discriminate between two different cytokines. Nerve impulses recorded from the vagus nerve of mice exposed to IL-1B and TNF were sorted into groups based on their shape and amplitude, and their respective firing rates were computed. These cytokine-mediated responses were subsequently decoded....
- Subject
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ElectrophysiologymiceVagus Nerve
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Blood-brain barrier deterioration and hippocampal gene expression in polymicrobial sepsis: an evaluation of endothelial MyD88 and the vagus nerve
Internal Dataset- Authors
- Gerard HonigSimone MaderHuiyi ChenAmit Porat4 more author(s)...
- Description
Systemic infection can initiate or exacerbate central nervous system (CNS) pathology, even in the absence of overt invasion of bacteria into the CNS. Recent epidemiological studies have demonstrated that human survivors of sepsis have an increased risk of long-term neurocognitive decline. There is thus a need for improved understanding of the physiological mechanisms whereby acute sepsis affects the...
- Subject
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miceVagus Nerve
- Access Rights
- Free to All
- Local Expert
- Betty DiamondBruce Volpe
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